Millimeters Matter - What You Need To Know About Organ Motion During Prostate Radiation Therapy


Organ Motion is Prevalent, Variable, and Unpredictable

Organ motion is prevalent, variable, and unpredictable during radiation therapy. It presents challenges to delivering precise external beam radiation to the prostate. A recent multi-institutional study showed that patients experienced organ motion during treatment fractions and the direction and degree of the motion is highly variable from patient to patient and day to day. The common methods used for target localization cannot provide continuous, real-time, objective guidance to clinicians managing patients receiving radiation therapy treatments. The Calypso® 4D Localization System™ and implanted Beacon® electromagnetic transponders provide improvements with continuous, real-time tumor setup and monitoring without the use of additional ionizing radiation, GPS for the Body®.

Prostate motion documented in the daily report demonstrates motion of the prostate of greater than 1cm over 6 minutes.



The Calypso® 4D Localization System™ is the first and only target localization method that is continuous, real-time, objective, highly accurate, and does not require ionizing radiation for treatment setup. Providing safe, accurate and effective localization, the Calypso System has been studied for safety and efficacy in over 2000 radiation therapy treatment sessions and has been cleared by the FDA for treatment setup and monitoring the position of the prostate during radiation therapy.

The Calypso® 4D Localization System™ and a Beacon® electromagnetic transponder.


Simple and Efficient Outpatient Implantation Procedure

The implantation of the Beacon® electromagnetic transponders is a simple and efficient outpatient procedure. Three Beacon® transponders are implanted in the prostate similar to gold marker implantation. This implantation procedure has established CPT® codes. The Calypso® 4D Localization System™ works with the implanted Beacon® electromagnetic transponders to provide continuous, real-time objective tracking, allowing therapy delivery to be managed more effectively.

Three implanted Beacon® electromagnetic transponders within the prostate.

This content is also available as a PDF for printing.

download PDF